There have been multiple occasions where I made cables for folks who requested they be built to the rane standard (pin one connected on one end only) and in all cases the cables have produced hum that was only cured by connecting pin 1 at both ends. Small sample size, but still...
Now if I were building shielded cables, which is to say cables that had both a conductor for pin 1 and also a shield, I would only connect the shield at one end.