My comment is specific to treatment in the US and our "unique" healthcare systems. There are many syndromes where there are simply a multiplicity of routes that lead to the symptoms manifesting themselves. In the US, and in my experience, many of the physicians either do not spend the time talking and actually listening to their patients. The old time family practitioner is rare. Sometimes knowing the patient is necessary in disentangling the cause. We went through a whole serious of practitioners with our sons IGA nephropathy until we actually found that listened to what we actually told them.