sure. I get to choose the setup and you can choose what you mean by "large differences in capacitance".
My key ingredients are a turntable, two cartridges, a step-up transformer, and a 70dB+ gain phono stage with MM switch. In this case, the cable is from the tonearm to either the step-up then to the MM option on the preamp, or the the MC input of the phono stage directly. Basic circuit would be similar to the ones in the below link, which also give an explanation on why capacitance is important and what it does to the resulting loading of the cartridge. Of course, since you specified "large" I would exaggerate things using the combination off the above equipment and probably roll of around 10kHz at a 3dB point. It would be very obvious.
Link: Hagerman Technology LLC: Cartridge Loading
Second setup would involve a pair of electrostatic headphones and the cable test would be in the headphone cable position. Key ingredient is a shitty as hell amplifier. Ray's A10 would probably work quite nicely.