Source:
HifiDIY CD Transport/Zapfiltered Twisted Pear Audio Opus DAC
Preamp:
PS Audio PCA-2
Amp/Speakers:
Paradigm Reference Active 20 (built in amps) and AV123 Rocket UFW-10 powered subwoofers (2)
Headphone Amp:
4 Channel Balanced β22 w/dual sigma22s in separate case
Headphones:
Modded AKG K340, Modded AKG K240 Sextette, Chocolate Donuts (Modded Yamaha YH-100 Orthodynamic drivers in custom wooden housings), Modded Sennheiser HD 580. All phones are cabled balanced
The chain is as follows...
The CD transport digital coax output is connected to the digital coax input of the Opus DAC. The Opus DAC balanced outputs are connected to the β22 balanced inputs. The β22 balanced outputs are connected to the PCA-2 balanced inputs. One pair of the PCA-2's balanced outputs are connected to the Paradigm Active 20's balanced inputs. The other pair of the PCA-2's balanced outputs are connected to the pair of AV123 Rocket UFW-10's balanced inputs.
I hear no buzz or ground loop through any of the headphones. I also hear no buzz or ground loop through the subwoofers. The only place I hear the buzz is through the speakers, and then it's only when the preamp is set on zero volume (where it automatically is set upon startup), or when I turn the preamp off (the speakers are always left on, but only power up upon receiving an input signal, same for the subwoofers).
The PS Audio PCA-2 does have some unique features, for example the active volume control. I'll link PS Audio's PCA-2 info page for reference.
http://www.psaudio.com/products/pca2_overview.asp