We already have a Harmony, and my wife likes it very much (she hated that we had, at one point, 5 or 6 remotes sitting on a coffee table). The problem still lies in that I haven't seen a power amp that can be turned on/off via remote.
HT rig has been mentioned and she wasn't exactly enamored with the idea of adding more speakers into the living room and doubt my current budget would allow for a decent HT rig.
As for a headphone rig, that's what I use the JH13 for, though I still need to get off my sick and lazy butt to send them back for a refit.